Nitrogen mustard compounds
Medchemexpress LLC Swertisin | 6991-10-2 | 5 MG
Swertisin is an oral adenosine A1 receptor antagonist and an SGLT2 inhibitor. It exhibits anti-diabetic and antioxidant properties, inhibits HBV, and improves cognitive and memory impairments in mice.
- Acts as an oral adenosine A1 receptor antagonist and SGLT2 inhibitor
- Exhibits anti-diabetic and antioxidant properties
- Inhibits HBV
- Improves cognitive and memory impairments
- Inhibits glucose uptake in HEK293 cells
- Suppresses HBsAg, HBeAg, and HBV DNA levels
- Reduces SGLT2 expression and lowers blood sugar in vivo
Medchemexpress LLC Toringin | 1329-10-8 | 99.6% | 416.38 g/mol | C21H20O9 | 10 MG
Toringin is a natural bioflavonoid isolated from the bark of Docyniopsis tschonoski, supplied for research use as a white-to-yellow solid (CAS 1329-10-8). The compound is offered in small research pack sizes and is accompanied by a product data sheet and safety data sheet.
- Natural bioflavonoid isolated from Docyniopsis tschonoski.
- White to yellow solid suitable for analytical and biological research.
- Reported high purity (approximately 99.6%).
- Supplied as a 10 mg vial for small-scale experiments.
- Documentation available: product data sheet and safety data sheet.
- Recommended storage: powder at -20°C; in solvent, -80°C for long-term storage.
Medchemexpress LLC Ascr#18 | 1355681-10-5 | 5 MG
Ascr#18 is an ascaroside that functions as a hormone in nematodes and is expressed during nematode development. It enhances resistance in various plants such as Arabidopsis, tomato, potato, and barley against viral, bacterial, oomycete, fungal, and nematode infections.
- Functions as a hormone in nematodes
- Expressed during nematode development
- Enhances resistance in various plants (Arabidopsis, tomato, potato, barley)
- Provides resistance against viral, bacterial, oomycete, fungal, and nematode infections
- Improves pathogen resistance and activates defense responses in Arabidopsis (in vitro studies)
Medchemexpress LLC Epoxymicheliolide | 1343403-10-0 | MFCD28387434 | 99.8% | 264.32 g·mol-1 | C15H20O4 | 10 MG
Epoxymicheliolide is a micheliolide-derived small molecule supplied for research use. It is characterized by CAS 1343403-10-0, molecular formula C15H20O4, and a molecular weight of 264.32 g·mol-1. The compound is provided at high purity and is intended for biochemical and cellular studies; documentation such as COA, SDS, and a product datasheet are available to support use and safety.
- High purity suitable for research (>99.8%).
- Supplied in small milligram quantities for laboratory experiments.
- Characterized by CAS 1343403-10-0 and formula C15H20O4.
- Documentation available: COA, SDS, and product datasheet.
eMolecules Ambeed / 4-Acetylpyridine / 10g / 490549457 / A284316 / / 1122-54-9 / MFCD00006433 / 121.139 / C7H7NO
Ambeed / 4-Acetylpyridine / 10g / 490549457 / A284316 / / 1122-54-9 / MFCD00006433 / 121.139 / C7H7NO
Medchemexpress LLC Toringin | 1329-10-8 | 5 MG
Toringin is a bioflavonoid isolated from the bark of Docyniopsis tschonoski. It decreases the cis-effect of expanded CTG repeats and cytotoxicity, and rescues PC12 neuronal cells when exposed to isosakuranetin. As a flavonoid, Toringin exhibits various biological activities beneficial against conditions such as cancers and coronary heart disease, and is effective in ameliorating RNA gain of function caused by expanded CTG repeats.
- Decreases cis-effect of expanded CTG repeats
- Decreases cytotoxicity
- Rescues PC12 neuronal cells
- Ameliorates RNA gain of function
- Exhibits various biological activities
- Beneficial against cancers and coronary heart disease
Medchemexpress LLC ZL0580 | 2377151-10-3 | 99.4% | 532.53 | 10 MG
ZL0580, an analog of ZL0590, epigenetically suppresses HIV by binding to the BD1 domain of BRD4. It inhibits Tat transactivation and transcription elongation, and also induces a repressive chromatin structure at the HIV promoter.
- Induces HIV transcriptional suppression.
- Exhibits low toxicity.
- Suppresses both PMA-stimulated and basal HIV transcription.
- Does not cause significant cell death at concentrations below 40 μM.
- Suppresses HIV in primary CD4+ T cells.
Medchemexpress LLC N-Methylmoranoline | 69567-10-8 | 177.20 | 5 MG
N-Methylmoranoline is a chemical substance identified by CAS No. 69567-10-8, with a molecular formula of C7H15NO4 and a molecular weight of 177.20. It appears as a white to off-white solid with a purity of 99.0% (HPLC). This product is stable under recommended storage conditions and is intended for laboratory research use.
- White to off-white solid appearance
- Purity of 99.0% by HPLC
- Molecular formula of C7H15NO4
- Molecular weight of 177.20
- Stable under recommended storage conditions
- Powder storage at -20°C for 3 years
- Solution storage at -80°C for 6 months or -20°C for 1 month
- Identified by CAS No. 69567-10-8
Medchemexpress LLC Lanoconazole | 101530-10-3 | MFCD00865590 | 98.0% | 319.8 g/mol | C14H10ClN3S2 | 5 MG
Lanoconazole is an imidazole-class antifungal research compound supplied as a solid reference standard for laboratory and pharmacological studies. It is used in in vitro and in vivo antifungal testing and mechanistic studies that inhibit sterol 14α-demethylase.
- Imidazole-class antifungal compound
- High purity suitable for analytical use
- Provided as a solid for easy handling and storage
- Available in small quantities ideal for research
- Well characterized molecular properties for reference
Medchemexpress LLC KB-5492 (anhydrous) | 129200-10-8 | 99.5% | 546.57 | 5 MG
KB-5492 anhydrous is a potent and selective inhibitor of the sigma receptor, inhibiting specific [3H]1,3-di(2-tolyl)guanidine (DTG) binding with an IC50 of 3.15 μM. It also functions as an anti-ulcer agent, preventing ethanol- and acidified aspirin-induced increases in 51Cr release from gastric epithelial cells in vitro, and macroscopic lesions in the gastric mucosa in vivo.
- Potent and selective sigma receptor inhibitor
- Inhibits specific DTG binding in a concentration-dependent manner
- Prevents ethanol- and acidified aspirin-induced increases in 51Cr release from gastric epithelial cells
- Prevents macroscopic lesions in the gastric mucosa in animal models
- Suitable for research use only
Medchemexpress LLC ZL0580 | 2377151-10-3 | 99.4% | 532.53 | 50 MG
ZL0580 is a structurally similar analog of ZL0590. It induces epigenetic suppression of HIV by selectively binding to the BD1 domain of BRD4. This compound suppresses HIV by inhibiting Tat transactivation and transcription elongation, and by inducing repressive chromatin structure at the HIV promoter. It is intended for research use only.
- Induces epigenetic suppression of HIV
- Selectively binds to BD1 domain of BRD4
- Inhibits Tat transactivation and transcription elongation
- Induces repressive chromatin structure at the HIV promoter
- Demonstrates low toxicity at effective concentrations (e.g., 8 μM in PBMCs)
- Suppresses both PMA-stimulated and basal HIV transcription
- Shows almost complete loss of productive HIV infection in CD4+ T cells at 8 μM
Medchemexpress LLC VIT-2763 | 2095668-10-1 | 99.9% | 408.43 | 50 MG
VIT-2763 is an oral ferroportin inhibitor designed to inhibit hepcidin binding to ferroportin and block iron efflux. It holds potential for treating β-thalassemia by addressing iron regulation. This compound has demonstrated significant biological activity both in vitro and in vivo.
- Reduces fluorescence polarization signal by displacing TMR-hepcidin from ferroportin.
- Induces BLA reporter gene activity, increasing intracellular iron concentrations by blocking iron export.
- Triggers ubiquitination and degradation of ferroportin.
- Corrects anemia and improves red blood cell parameters in relevant animal models.
- Decreases the percentage of ROS-positive red blood cells and extends their lifespan.
- Significantly decreases serum iron levels in animal studies.
- Currently undergoing Phase 2 clinical trials for Beta-Thalassemia and Sickle Cell Disease.
Medchemexpress LLC Methyl (4-((4-fluorobenzyl)(prop-2-yn-1-yl)amino)-2,6-dimethylphenyl)carbamate | 1821222-10-9 | MFCD34676457 | 99.5% | C20H21FN2O2 | 10MG
HN37 is a small-molecule KCNQ2 (Kv7) activator intended for laboratory research use. It exhibits potent neuronal Kv7 activation with reported antiepileptic activity (EC50 ≈ 37 nM) and contains an alkyne functional group that enables copper-catalyzed azide-alkyne cycloaddition (CuAAC) for bioconjugation and probe synthesis. The compound is provided as a high-purity solid or DMSO solution for experimental use.
- Potent KCNQ2 (Kv7) activator with EC50 ≈ 37 nM.
- Contains an alkyne group for CuAAC click chemistry.
- High purity (99.53%) suitable for research applications.
- Supplied in solid and DMSO solution formats.
- Intended for laboratory research only; not for human use.